Clinical Studies

More than 100 articles and studies on EECP have been published in leading cardiology journals, all supporting the treatment's safety and effectiveness. We hope you find this sampling helpful, and we will continue to update this section as often as possible. Predictors of benefit in angina patients one year after completing enhanced external counterpulsation: initial responders to treatment versus nonresponders. - Lawson WE, Hui JC, Kennard ED, Barsness G, Kelsey SF; IEPR investigators. An update on enhanced external counterpulsation.  - Shea ML, Conti CR, Arora RR. Clinical Cardiology. 2005 Mar;28(3):115-8. Review. Enhanced external counterpulsation: a new technique to augment renal function in liver cirrhosis. - Werner D, Tragner P, Wawer A, Porst H, Daniel WG, Gross P. Nephrology, Dialysis, Transplantation. 2005 May;20(5):920-6. Epub 2005 Mar 23. Enhanced External Counterpulsation. - Brosche TA, Middleton SK, Boogaard RG. Dimensions of Critical Care Nursing. 2005 September/October;23(5):208-214. Enhanced external counter pulsation (EECP) as a novel treatment for restless legs syndrome (RLS): a preliminary test of the vascular neurologic hypothesis for RLS. - Rajaram SS, Shanahan J, Ash C, Walters AS, Weisfogel G. Sleep Medicine. 2005 Mar;6(2):101-6. Epub 2005 Jan 24. Angina patients with diastolic versus systolic heart failure demonstrate comparable immediate and one-year benefit from enhanced external counterpulsation. - Lawson WE, Silver MA, Hui JC, Kennard ED, Kelsey SF. Journal of Cardiac Failure. 2005 Feb;11(1):61-6. Frequency and efficacy of repeat enhanced external counterpulsation for stable angina pectoris (from the International EECP Patient Registry). - Michaels AD, Barsness GW, Soran O, Kelsey SF, Kennard ED, Hui JC, Lawson WE; International EECP Patient Registry Investigators. American Journal of Cardiology. 2005 Feb 1;95(3):394-7. Effects of enhanced external counterpulsation on hemodynamics and its mechanism. - # Taguchi I, Ogawa K, Kanaya T, Matsuda R, Kuga H, Nakatsugawa M. # Circulation Journal. 2004 Nov;68(11):1030-4. Effectiveness of enhanced external counterpulsation in patients with left main disease and angina. - Lawson WE, Hui JC, Barsness GW, Kennard ED, Kelsey SF; IEPR Investigators. Clinical Cardiology. 2004 Aug;27(8):459-63. Accelerated reperfusion of poorly perfused retinal areas in central retinal artery occlusion and branch retinal artery occlusion after a short treatment with enhanced external counterpulsation. - Werner D, Michalk F, Harazny J, Hugo C, Daniel WG, Michelson G. Retina. 2004 Aug;24(4):541-7. Enhanced external counterpulsation improves skin oxygenation and perfusion. - Hilz MJ, Werner D, Marthol H, Flachskampf FA, Daniel WG. European Journal of Clinical Investigations. 2004 Jun;34(6):385-91. Successful treatment of symptomatic coronary endothelial dysfunction with enhanced external counterpulsation. - Bonetti PO, Gadasalli SN, Lerman A, Barsness GW. Mayo Clinic Proceedings. 2004 May;79(5):690-2. Two-year outcomes after enhanced external counterpulsation for stable angina pectoris (from the International EECP Patient Registry [IEPR]). - Michaels AD, Linnemeier G, Soran O, Kelsey SF, Kennard ED. American Journal of Cardiology. 2004 Feb 15;93(4):461-4. A New Treatment Modality in Heart Failure Enhanced External Counterpulsation (EECP) - Soran O. Cardiology in Review. 2004 Jan-Feb;12(1):15-20. Enhanced External Counterpulsation as Initial Revascularization Treatment for Angina Refractory to Medical Therapy - Fitzgerald CP, Lawson WE, Hui JC, Kennard ED; IEPR Investigators. Cardiology. 2003;100(3):129-35. Enhanced External Counterpulsation and Functional Improvement in Octogenarians with Symptomatic Ischemic Heart Disease - Braverman D, Wechsler B. Archives of Physical Medicine and Rehabilitation. 2003 Sept;84(9):A10. Enhanced External Counterpulsation in the Management of Angina in the Elderly - Linnemeier G, Michaels AD, Soran O, Kennard ED; International EECP Registry (IEPR) Investigators. American Journal of Geriatric Cardiology. 2003 Mar-Apr;12(2):90-6. Ongoing and Planned Studies of Enhanced External Counterpulsation - Conti CR. Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II26-28. Treatment Options for Angina Pectoris and the Future Role of Enhanced External Counterpulsation - Holmes DR Jr. Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II22-25. Current Use of Enhanced External Counterpulsation and Patient Selection - Lawson WE. Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II16-21. Enhanced External Counterpulsation: Mechanism of Action - Feldman AM. Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II11-15. A Review of Enhanced External Counterpulsation Clinical Trials - Beller GA. Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II6-10. A Historical Overview of Enhanced External Counterpulsation - DeMaria AN. # Clinical Cardiology. 2002 Dec;25(12 Suppl 2):II3-5. Enhanced External Counterpulsation as Treatment for Chronic Angina in Patients with Left Ventricular Dysfunction: A Report from the International EECP Patient Registry (IEPR) - Soran O, Kennard ED, Kelsey SF, Holubkov R, Strobeck J, Feldman AM. Congestive Heart Failure. 2002 Nov-Dec;8(6):297-302. Left Ventricular Systolic Unloading and Augmentation of Intracoronary Pressure and Doppler Flow During Enhanced External Counterpulsation - Michaels AD, Accad M, Ports TA, Grossman W. Circulation. 2002 Sep 3;106(10):1237-1242. Enhanced External Counterpulsation in Patients with Heart Failure: A Multicenter Feasibility Study - Soran O, Fleishman B, Demarco T, Grossman W, Schneider VM, Manzo K, de Lame PA, Feldman AM. Congestive Heart Failure. 2002 Jul-Aug;8(4)204-8, 227. Relation of the Pattern of Diastolic Augmentation During a Course of Enhanced External Counterpulsation (EECP) to Clinical Benefit [from the International EECP Patient Registry (IEPR)] - Lakshmi MV, Kennard ED, Kelsey SF, Holubkov R, Michaels AD. American Journal of Cardiology. 2002 Jun 1;89(11):1303-1305. Comparison of Patients Undergoing Enhanced External Counterpulsation and Percutaneous Coronary Intervention for Stable Angina Pectoris - Holubkov R, Kennard ED, Foris JM, Kelsey SF, Soran O, Williams DO, Holmes Jr. DR. The American Journal of Cardiology. 2002 May 15;89:1182-1186.